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Record W3092823894 · doi:10.1002/oby.23005

BMI and All‐Cause Mortality in a Population‐Based Cohort in Rural South Africa

2020· article· en· W3092823894 on OpenAlexaff
Jennifer Manne‐Goehler, Kathy Baisley, Alain Vandormael, Till Bärnighausen, Frank Tanser, Kobus Herbst, Deenan Pillay, Mark J. Siedner

Bibliographic record

VenueObesity · 2020
Typearticle
Languageen
FieldMedicine
TopicHIV-related health complications and treatments
Canadian institutionsInstitute of Infection and Immunity
FundersNational Institute of Allergy and Infectious DiseasesNational Heart, Lung, and Blood InstituteNational Institute on AgingNational Institutes of HealthWellcome Trust
KeywordsVerbal autopsyMedicineHazard ratioOverweightDemographyCohortPopulationProportional hazards modelCause of deathObesityBody mass indexCohort studyProspective cohort studyInternal medicineEnvironmental healthConfidence intervalDisease

Abstract

fetched live from OpenAlex

Objective This study evaluates the association between BMI and all‐cause and cause‐specific mortality in South Africa. Methods Prospective, population‐based observational cohort data from rural South Africa were analyzed. BMI was measured in 2010. Demographic characteristics were recorded and deaths were verified with verbal autopsy interview. The InterVA‐5 tool was used to assign causes of death. HIV testing was conducted annually. Cox proportional hazards models were fit to estimate the effect of BMI on all‐cause and cause‐specific mortality, accounting for the competing risk of death from other causes. Models were adjusted for sociodemographic characteristics and HIV status, and inverse probability weighting for survey nonparticipation was used. Results The cohort consisted of 9,728 individuals. In adjusted models, those with BMI of 25.0 to 29.9 kg/m 2 or 30.0 to 34.9 kg/m 2 had a lower hazard of death (adjusted hazard ratio: 0.80; 95% CI: 0.69‐0.92 and adjusted hazard ratio: 0.75; 95% CI: 0.60‐0.93, respectively) compared with those with BMI of 18.5 to 24.9 kg/m 2 . Conclusions Individuals in South Africa who meet clinically defined criteria for overweight or obesity had a lower risk of all‐cause mortality than those with a normal BMI. These findings were stronger for women and communicable conditions.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.004
Threshold uncertainty score0.298

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.047
GPT teacher head0.323
Teacher spread0.276 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations23
Published2020
Admission routes1
Has abstractyes

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