Dynamic remodeling of white adipose tissue by intermittent fasting
Why this work is in the frame
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Bibliographic record
Abstract
Excessive accumulation of white adipose tissue (WAT) is a hallmark of obesity and perturbs systemic metabolism. Intermittent Fasting (IF) is a periodic and repeated energy restriction strategy utilized to combat obesity and improve metabolic parameters. Many studies have shown that one of the main targets of IF is WAT. This heterogenous organ is sensitive to nutritional conditions and undergoes dynamic remodeling to mediate IF benefits. In this review, we aim to discuss the impact of IF on various WAT cell components including adipocytes, adipocyte precursor cells (APCs), immune cells, and vascular cells. Furthermore, we highlight areas of research that require further exploration and propose overarching mechanisms that may mediate IF benefits observed in preclinical models.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it