Acute Reversible Motor Predominant Polyradiculoneuropathy among Thai Prisoners after the Outbreak of H3N2 Influenza: A Case Series
Bibliographic record
Abstract
Objective: This study aims to describe the clinical, laboratory and electrophysiological findings of the prisoners who developed acute reversible motor predominant polyradiculoneuropathy after the outbreak of H3N2 influenza. Material and Methods: Among H3N2 infected Thai prisoners, all patients with acute flaccid weakness were included in this retrospective case series. We analyzed the results of electromyography (EMG), cerebrospinal fluid analysis, and serum levels of antiganglioside antibodies, folate, thiamine, and vitamin B12.Results: Among 262 H3N2 influenza patients, motor predominant polyradiculoneuropathy predominantly affecting the lower limbs developed in 10 patients. EMG revealed significantly decreased compound muscle action potentials with preserved distal latencies and conduction velocities in the peroneal nerves. Early fibrillation potentials were demonstrated on EMG performed 12-14 days post-onset of symptoms. The cerebrospinal fluid study showed normal profiles. All laboratory results appeared normal except for the significantly low mean±standard deviation serum folate level of 1.80± 0.78 [reference value 3.89–26.80 nanograms per milliliter (ng/mL)] as compared to the mean serum folate level in the normal Thai population of 10.80 ng/mL (p-value<0.001, 95% confidential interval -9.55 to -8.45). All patients were treated with 15 milligram per day of folic acid and all patients improved clinically. Conclusion: Although the relationship between low plasma folate level and polyradiculoneuropathy is unclear, a superimposed folate deficiency contributing to the pathophysiology is possible.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.010 | 0.004 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.000 | 0.003 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".