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Record W3097286420 · doi:10.31584/jhsmr.2020769

Acute Reversible Motor Predominant Polyradiculoneuropathy among Thai Prisoners after the Outbreak of H3N2 Influenza: A Case Series

2020· article· en· W3097286420 on OpenAlexaff
Phichamon Khanittanuphong, Thanyalak Amornpojnimman, Sirichai Cheewatanakornkul, Watchara Viratyaporn, Ittipon Preechawettayakul, Chorfa Buntong, Pat Korathanakhun, Erin O’Ferrall

Bibliographic record

VenueJournal of Health Science and Medical Research · 2020
Typearticle
Languageen
FieldMedicine
TopicInfectious Encephalopathies and Encephalitis
Canadian institutionsMcGill UniversityMontreal Neurological Institute and Hospital
FundersFaculty of Medicine, Prince of Songkla UniversityPrince of Songkla University
KeywordsPolyradiculoneuropathyMedicineCerebrospinal fluidWeaknessInternal medicineGastroenterologyConfidence intervalAnesthesiaGuillain-Barre syndromeSurgeryPediatrics

Abstract

fetched live from OpenAlex

Objective: This study aims to describe the clinical, laboratory and electrophysiological findings of the prisoners who developed acute reversible motor predominant polyradiculoneuropathy after the outbreak of H3N2 influenza. Material and Methods: Among H3N2 infected Thai prisoners, all patients with acute flaccid weakness were included in this retrospective case series. We analyzed the results of electromyography (EMG), cerebrospinal fluid analysis, and serum levels of antiganglioside antibodies, folate, thiamine, and vitamin B12.Results: Among 262 H3N2 influenza patients, motor predominant polyradiculoneuropathy predominantly affecting the lower limbs developed in 10 patients. EMG revealed significantly decreased compound muscle action potentials with preserved distal latencies and conduction velocities in the peroneal nerves. Early fibrillation potentials were demonstrated on EMG performed 12-14 days post-onset of symptoms. The cerebrospinal fluid study showed normal profiles. All laboratory results appeared normal except for the significantly low mean±standard deviation serum folate level of 1.80± 0.78 [reference value 3.89–26.80 nanograms per milliliter (ng/mL)] as compared to the mean serum folate level in the normal Thai population of 10.80 ng/mL (p-value<0.001, 95% confidential interval -9.55 to -8.45). All patients were treated with 15 milligram per day of folic acid and all patients improved clinically. Conclusion: Although the relationship between low plasma folate level and polyradiculoneuropathy is unclear, a superimposed folate deficiency contributing to the pathophysiology is possible.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: Case report
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.008

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0020.001
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.051
GPT teacher head0.392
Teacher spread0.341 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designCase report
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2020
Admission routes1
Has abstractyes

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