Maculopapular Rash Related to Atomoxetine: Case Report
Bibliographic record
Abstract
Exanthematous drug eruptions, also known as maculopapular drug eruptions, are the most common drug-induced hypersensitivity reactions. Pruritus, urticaria, exanthematous rash, fixed drug eruption, photosensitivity, pigmentation and alopecia are common skin reactions to psychotropic medications. Atomoxetine (ATX), a selective inhibitor of presynaptic norepinephrine transporters (SNRI), is classified as a non-stimulant and is commonly used in the treatment of attention deficit hyperactivity disorder (ADHD). It also binds to dopamine and serotonin transporters with a low affinity. Abdominal pain, loss of appetite, somnolence, irritability, fatigue, dizziness and dyspepsia are the most common side effects of ATX. Major cutaneous drug reactions with SNRIs are rarely reported in the literature. Here we present an eight-year-old girl diagnosed with ADHD who had a drug-induced skin reaction after an increase in the dosage of ATX treatment.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.002 | 0.001 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.002 | 0.001 |
| Science and technology studies | 0.003 | 0.001 |
| Scholarly communication | 0.001 | 0.002 |
| Open science | 0.001 | 0.001 |
| Research integrity | 0.004 | 0.004 |
| Insufficient payload (model declined to judge) | 0.004 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".