Investigations of Sliding-Induced Solute Transport in Articular Cartilage
Bibliographic record
Abstract
Solute transport has not been studied in articular cartilage subject to sliding loads, as occurs in vivo.Therefore, the goal of this thesis is to provide a comprehensive investigation of solute transport under sliding loads specifically investigating enhancement to mass transfer and spatiotemporal changes to diffusivity within the tissue.The findings are contextualized by supplemental investigations comparing the results to commonly studied loading modes such as uniaxial compression, elucidating the role of the superficial region as a barrier to load induced solute transport, and the accuracy of nutrient diffusion models (single vs multi-layer) for characterizing diffusivity.This study demonstrates that mass transfer is higher for sliding compared to uniaxial compression reaching 4.4-fold at 2 hrs (p=0.002) and this can exceed the passive capacity of the tissue.In addition, this work demonstrates a spatiotemporal dependence of diffusivity within the tissue under sliding loads.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".