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A lentinan-loaded hydrogel with core-shell structure induces broad-spectrum resistance against plant virus by activating the expression of CML30

2020· preprint· en· W3102757246 on OpenAlexaff
Shunyu Xiang, Xue Chen, Jing Wang, Haoran Peng, Xing Lv, Long Jiang, Zhe Cao, Jin Huang, Daibin Wang, Lisong Ma, Xianchao Sun

Bibliographic record

Venuenot available
Typepreprint
Languageen
FieldAgricultural and Biological Sciences
TopicPlant Virus Research Studies
Canadian institutionsAgriculture and Agri-Food Canada
FundersFundamental Research Funds for the Central UniversitiesChina National Tobacco CorporationNational Natural Science Foundation of China
KeywordsLentinanTobacco mosaic virusChemistryCalciumPotato virus XChitosanBiophysicsPlant cellVirusPlant virusCell biologyBiochemistryBiologyVirologyPolysaccharide

Abstract

fetched live from OpenAlex

Control of plant virus disease largely depends on the induced plant defense achieved by the external application of synthetic chemical inducers with the ability to modify defense-signaling pathways. However, most of the molecular mechanisms underlying these inducers remain unknown. Here, we developed a lentinan-loaded hydrogel with the core-shell structure and discovered how it protects plant from different virus infections. The hydrogel was synthesized by adding a chitosan shell on the surface of the sodium alginate-calcium ion-lentinan (LNT) hydrogel (SL-gel) to form CSL-gel. CSL-gel exhibits the capacity of prolonging the stable-release of lentinan and promoting calcium ions release. Application of CSL-gel on the root of plants significantly promotes plant growth and development and induces broad-spectrum resistance against TMV, TuMV, PVX and TRV. Furthermore, we found that the sustained release of calcium ions from the CSL-gel triggers the high expression of cal-modulin-like protein 30 (CML30), and silencing of CML30 enhances the susceptibility of tobacco to TMV. Our findings provide evidence that the novel and synthetic CSL-gel with the sustainable release of LNT and calcium ion strongly inhibits the plant virus infection. This study uncovers a novel mode of action by which CSL-gel with the stable release of calcium ion triggers CML30 expression.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.003

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.046
GPT teacher head0.249
Teacher spread0.203 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations1
Published2020
Admission routes1
Has abstractyes

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