168 Nursery diets formulated with deoxynivalenol-contaminated corn reduced growth performance but did not modulate the cutaneous hypersensitivity response to ovalbumin or candida albicans
Bibliographic record
Abstract
Abstract A total of 144 newly weaned pigs (21 days of age) were used to determine the effect of deoxynivalenol (DON)-contaminated corn, with or without NutraMix™ supplementation, on growth performance and indices of immune system functionality during the nursery period. Pigs were randomly allocated to 24 pens of six pigs and assigned to 1 of 4 dietary treatments according to a 2X2 factorial design (n=6); treatments were fed for the 43±1-day nursery period in three phases (phases I, II, and III fed for 8, 14, and 21±1 days, respectively). The factors were clean or DON-contaminated corn and with (2 g/kg in complete diet) or without NutraMix™ supplementation. The DON diets were formulated to ensure a step-up in DON concentration for each phase (3, 4, and 5 ppm in phases I, II, and III, respectively; analyzed concentrations were 3, 3 and 4 ppm). Individual pig body weights and per pen feed intake were recorded weekly. Two pigs per pen were vaccinated against ovalbumin and candida albicans to measure humoral and cell-mediated immune responses by the cutaneous hypersensitivity response test. The ADG (600 vs 693±28 g) and ADFI (979 vs 1110±51 g) in phase III and final BW (25.2 vs 27.1±0.9 kg) were reduced for pigs fed contaminated corn (P< 0.005, P=0.088, and P< 0.05, respectively). NutraMix™ supplementation tended (P=0.086) to improve ADFI (181 vs 142±14 g) in the first week after weaning. All pigs responded to both ovalbumin and candida albicans during the cutaneous hypersensitivity response (P< 0.05), but DON nor NutraMix™ influenced the response. The DON-contaminated diets had the greatest impact on pig growth performance during phase III and when DON concentration was 4 ppm, with no modulation of the cutaneous hypersensitivity response. NutraMix™ supplementation during the early weaning period may be a means to stimulate nursery pig feed intake.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.003 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".