MétaCan
Menu
Back to cohort
Record W3108152667 · doi:10.1158/1055-9965.epi-20-0732

Occupational Heat Exposure and Breast Cancer Risk in the MCC-Spain Study

2020· article· en· W3108152667 on OpenAlexaff
Alice Hinchliffe, Manolis Kogevinas, Beatriz Pérez‐Gómez, Eva Ardanáz, Pilar Amiano, Alba Marcos‐Delgado, Gemma Castaño‐Vinyals, Javier Llorca, Vı́ctor Moreno, Juan Alguacil, Guillermo Fernández‐Tardón, Dolores Salas, Rafael Marcos‐Gragera, Núria Aragonés, Marcela Guevara, Leire Gil, Vicente Martín, Yolanda Benavente, Inés Gómez‐Acebo, Miguel Santibáñez, Miguel Ángel Baeza Alba, Ana M. García, Marina Pollán, Michelle C. Turner

Bibliographic record

VenueCancer Epidemiology Biomarkers & Prevention · 2020
Typearticle
Languageen
FieldEnvironmental Science
TopicClimate Change and Health Impacts
Canadian institutionsUniversity of Ottawa
FundersDepartment of Chemical Engineering, Monash UniversityDepartament d'Universitats, Recerca i Societat de la InformacióInstituto de Salud Carlos IIIGeneralitat de CatalunyaMinisterio de Ciencia e InnovaciónUniversidad de OviedoGeneralitat ValencianaJunta de AndalucíaEuropean CommissionFundación Marqués de ValdecillaCentres de Recerca de CatalunyaJunta de Castilla y LeónMinisterio de Ciencia, Innovación y Universidades
KeywordsBreast cancerMedicineConfoundingWet-bulb globe temperatureConfidence intervalJob-exposure matrixCancerPopulationOccupational medicineCase-control studyExposure assessmentOccupational exposureDemographyInternal medicineEnvironmental healthHeat stressBiology

Abstract

fetched live from OpenAlex

BACKGROUND: Mechanisms linking occupational heat exposure with chronic diseases have been proposed. However, evidence on occupational heat exposure and cancer risk is limited. METHODS: ≥ 25% for at least 1 year) and work time with heat stress (wet bulb globe temperature ISO 7243) for each occupation. We used three exposure indices: ever versus never exposed, lifetime cumulative exposure, and duration of exposure (years). We estimated ORs and 95% confidence intervals (CI), applying a lag period of 5 years and adjusting for potential confounders. RESULTS: = 0.01 and 0.03, respectively). Stronger associations were found for hormone receptor-positive disease (OR ever exposure = 1.38; 95% CI, 1.12-1.67). We found no confounding effects from multiple other common occupational exposures; however, results attenuated with adjustment for occupational detergent exposure. CONCLUSIONS: This study provides some evidence of an association between occupational heat exposure and female breast cancer risk. IMPACT: Our results contribute substantially to the scientific literature. Further investigations are needed considering multiple occupational exposures.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.062
Threshold uncertainty score0.123

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0000.001
Research integrity0.0010.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.106
GPT teacher head0.394
Teacher spread0.288 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations17
Published2020
Admission routes1
Has abstractyes

Explore more

Same venueCancer Epidemiology Biomarkers & PreventionSame topicClimate Change and Health ImpactsFrench-language works237,207