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Non-uniform refinement: adaptive regularization improves single-particle cryo-EM reconstruction

2020· article· en· 1,859 citations· W3108495343 on OpenAlex· 10.1038/s41592-020-00990-8

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian affiliationAn author listed a Canadian institution. This is the only route the usual frame has.
Canadian funderA Canadian agency funded it. The work may carry no Canadian affiliation at all.

Abstract

No abstract. This is not a gap in this database — OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

The record

Venue
Nature Methods
Topic
Advanced Electron Microscopy Techniques and Applications
Field
Biochemistry, Genetics and Molecular Biology
Canadian institutions
Vector InstituteCanadian Sugar InstituteUniversity of Toronto
Funders
Vector InstituteNatural Sciences and Engineering Research Council of CanadaGovernment of CanadaCanadian Institute for Advanced Research
Keywords
Regularization (linguistics)AlgorithmComputer scienceParticle (ecology)Computational biologyBiological systemPhysicsArtificial intelligenceBiology
Has abstract in OpenAlex
no