PSVII-33 Inter-Animal Variability in Androstenone Transport and the Potential Effect on the Development of Boar Taint
Bibliographic record
Abstract
Abstract Boar taint is a meat quality issue characterized by an off-odour or off-flavour in pork caused by the accumulation of androstenone in the fat. Our previous work demonstrated that androstenone binds non-specifically to albumin in the plasma and suggested that the binding affinity of androstenone might vary between individual animals, which may affect the subsequent development of boar taint. Therefore, the purpose of this study was to characterize the binding of androstenone in the plasma of animals with high and low fat androstenone concentrations to determine the effect of androstenone binding affinity on the development of boar taint. Plasma and backfat samples were obtained from 5-month-old terminal cross [Duroc x (Landrace x Yorkshire)] (n = 8) boars. An androstenone specific enzyme-linked immunosorbent assay (ELISA) was used to determine animals with high (n = 4) or low (n = 4) fat androstenone concentrations. The plasma from each boar was incubated with radiolabeled [3H]-androstenone in the presence or absence of excess unlabeled androstenone. Excess unlabeled androstenone created competition for binding sites allowing the displacement of [3H]-androstenone from albumin to be quantified. Incubations were analyzed by a novel high-performance liquid chromatography (HPLC) method we previously developed to assess androstenone binding. Statistical analysis was conducted using a two-way ANOVA. The plasma albumin concentrations were similar across individual boars; however, the percentage of androstenone that could be displaced from albumin in boars with high fat androstenone concentrations ranged from 7.1 ± 2.4% to 21.9 ± 5.2%, and was significantly lower (P = 0.01) than the percentage of androstenone displaced in the animals with low fat androstenone concentrations. These results suggest that the binding affinity of androstenone is inversely related with fat androstenone concentrations, demonstrating for the first time that the transport of androstenone in the plasma may contribute to the development of boar taint.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.001 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".