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Record W3111083740 · doi:10.17863/cam.59912

Association between DNA methylation and ADHD symptoms from birth to school age: a prospective meta-analysis.

2020· article· en· W3111083740 on OpenAlexafffund
Alexander Neumann, Esther Walton, Silvia Alemany, Charlotte A. M. Cecil, Juan R. González, Dereje D. Jima, Jari Lahti, Samuli Tuominen, Edward D. Barker, Elisabeth B. Binder, Doretta Caramaschi, Ángel Carracedo, Darina Czamara, Jorunn Evandt, Janine F. Felix, Bernard F. Fuemmeler, Kristine B. Gützkow, Cathrine Hoyo, Jordi Júlvez, Eero Kajantie, Hannele Laivuori, Rachel L. Maguire, Léa Maître, Susan K. Murphy, Mario Murcia, Pia Villa, Gemma C. Sharp, Jordi Sunyer, Katri Räikkönen, Marian J. Bakermans‐Kranenburg, Marinus H. van IJzendoorn, Mònica Guxens, Caroline L. Relton, Henning Tiemeier

Bibliographic record

VenueDuo Research Archive (University of Oslo) · 2020
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicEpigenetics and DNA Methylation
Canadian institutionsJewish General Hospital
FundersNational Institute of Diabetes and Digestive and Kidney DiseasesInstituto de Salud Carlos IIIBiotechnology and Biological Sciences Research CouncilNational Institutes of HealthCentre Hospitalier Universitaire de PoitiersEconomic and Social Research CouncilMinisterio de Asuntos Económicos y Transformación Digital, Gobierno de EspañaLastentautien TutkimussäätiöEmil Aaltosen SäätiöMedical Research CouncilSigne ja Ane Gyllenbergin SäätiöJuho Vainion SäätiöCanadian Institutes of Health ResearchJane ja Aatos Erkon SäätiöSuomen Lääketieteen SäätiöPäivikki ja Sakari Sohlbergin SäätiöHelse- og OmsorgsdepartementetNederlandse Organisatie voor Wetenschappelijk OnderzoekOpetus- ja KulttuuriministeriöNovo NordiskGeneralitat de CatalunyaErasmus Universiteit RotterdamZonMwInstitut National de la Santé et de la Recherche MédicaleHelsingin YliopistoEuropean CommissionU.S. Environmental Protection AgencyErasmus Medisch CentrumHelsingin ja Uudenmaan SairaanhoitopiiriDuke Cancer InstituteCentres de Recerca de CatalunyaKuopion Yliopistollinen SairaalaUniversity of BristolJoint Programming Initiative A healthy diet for a healthy lifeJalmari ja Rauha Ahokkaan Säätiö
KeywordsDNA methylationEpigeneticsMethylationAttention deficit hyperactivity disorderProspective cohort studyMedicineInternal medicineBioinformaticsGeneticsBiologyPsychiatryGene

Abstract

fetched live from OpenAlex

OpenAlex records an abstract for this work, but it could not be fetched just now.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.007
metaresearch head score (Gemma)0.012
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Meta-analysis · Consensus signal: Meta-analysis
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.018
Threshold uncertainty score0.037

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0070.012
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0050.023
Bibliometrics0.0020.004
Science and technology studies0.0010.000
Scholarly communication0.0020.001
Open science0.0010.001
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.057
GPT teacher head0.303
Teacher spread0.245 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designMeta-analysis
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2020
Admission routes2
Has abstractyes

Explore more

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