MétaCan
Menu
← Back to cohort
Record W3111243205 · doi:10.21203/rs.3.rs-19604/v1

Covariation of the gut microbiome with diet in Aves

2020· preprint· en· W3111243205 on OpenAlexaff
Kangpeng Xiao, Yutan Fan, Zhipeng Zhang, Xuejuan Shen, Xiaobing Li, Xianghui Liang, Ran Bi, Yajiang Wu, Junqiong Zhai, Junwei Dai, David M. Irwin, Wu Chen, Yongyi Shen

Bibliographic record

Venuenot available
Typepreprint
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGut microbiota and health
Canadian institutionsUniversity of Toronto
FundersHigher Education Discipline Innovation ProjectChinese Academy of EngineeringDepartment of Education of Guangdong ProvinceGuangdong Science and Technology DepartmentChinese Academy of SciencesDepartment of Agriculture of Guangdong ProvinceNational Natural Science Foundation of China
KeywordsGut microbiomeMicrobiomeBiologyZoologyEvolutionary biologyGenetics

Abstract

fetched live from OpenAlex

Abstract Background:Research over the past few decades has revealed a vital role for the gut microbiome in the health of various animals including birds. Multiple factors can influence the gut microbiome. Opportunistic feeding and multiple other environment factors can influence the results, and bias the conclusions, when wild animals are used to study the influence of phylogeny and diet on their gut microbiomes. Therefore, to study this question in this study, we collected fecal samples from 43 species of Aves at one time to avoid influences such as geography, weather, and season. Results:Approaches based on both 16S rRNA gene sequencing (135 samples) and whole metagenome shotgun sequencing (17 samples) were used. Our data show that diets containing native starch will increase the abundance of Lactobacillus in gut microbiome, while those containing plant-derived fiber will mainly enrich the levels of Clostridium. Greater numbers of Fusobacteria and Proteobacteria are detected in carnivorous birds, while in birds fed a commercial corn-soybean basal diet, a stronger inner-connected microbial community containing Clostridia and Bacteroidia was enriched. Furthermore, a microbial functional analysis based on the metagenomic sequences showed that the function of microbes was adapted to different food types to achieve the most beneficial state for the hosts. Conclusions:The covariation of diet and gut microbiome identified in our study demonstrates modulation of the gut microbiome by dietary diversity and expands our knowledge of diet-microbiome-host interactions in birds.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.006

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0010.000
Scholarly communication0.0010.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.012
GPT teacher head0.248
Teacher spread0.235 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2020
Admission routes1
Has abstractyes

Explore more

Same topicGut microbiota and health→French-language works237,207→