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Altered power spectra in antisocial males during rest as a function of cocaine dependence: A network analysis

2020· article· en· W3111258731 on OpenAlexaff
Isabelle Simard, William James Denomme, Matthew S. Shane

Bibliographic record

VenuePsychiatry Research Neuroimaging · 2020
Typearticle
Languageen
FieldPsychology
TopicMental Health Research Topics
Canadian institutionsUniversity of Ontario Institute of Technology
FundersNational Institute on Drug Abuse
KeywordsPsychologyAntisocial personality disorderCocaine dependenceJuvenile delinquencyClinical psychologyDevelopmental psychologyPsychiatryPoison controlInjury preventionAddictionMedicineMedical emergency

Abstract

fetched live from OpenAlex

Abnormalities in the spectral power of offenders' neural oscillations have been noted within select Resting-State Networks (RSNs); however, no study has yet evaluated the influence of cocaine dependence, drug use severity, and psychopathic traits on these abnormalities. To this end, the present study compared rest-related power spectral characteristics between two groups of offenders (with and without a DSM-IV-TR cocaine-dependence diagnosis) and a non-offender control group. Results indicated that both offender groups presented with lower low frequency power ratio (LFPR) scores (i.e. across all RSNs) than non-offenders. These differences in LFPR scores were due to both higher high-frequency power (0.15-0.25 Hz; within seven (in non-dependent offenders) and five (in cocaine-dependent offenders) of eight investigated networks) and decreased low-frequency power (0.01-0.10 Hz; within six (in non-dependent offenders) and one (in cocaine-dependent offenders) of eight investigated networks) compared to non-offenders. Thus, both cocaine-dependent and non-dependent offenders displayed abnormal neural oscillations, suggesting that these oscillatory abnormalities could exist as neurobiological features associated with offender status. Offenders' LFPR levels correlated with lifetime years of cocaine use, but not with the level of psychopathic traits. These findings supplement our knowledge regarding the influence of substance use on resting-state activity in offenders; moreover, they provide further indication of the importance of evaluating shared/unique variance associated with drug use and pyschopathic personality traits.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.004

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.106
GPT teacher head0.449
Teacher spread0.344 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2020
Admission routes1
Has abstractyes

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