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Record W3112330444 · doi:10.1007/978-3-030-47852-0_28

Journey into Genes: Cultural Values and the (Near) Future of Genetic Counselling in Mental Health

2020· book-chapter· en· W3112330444 on OpenAlexaff
David Crepaz‐Keay, Jehannine Austin, Lauren Weeks

Bibliographic record

Venuenot available
Typebook-chapter
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicBRCA gene mutations in cancer
Canadian institutionsUniversity of British Columbia Hospital
Fundersnot available
KeywordsNarrativeContext (archaeology)Mental healthSet (abstract data type)Narrative reviewClinical PracticeMental health careMental healthcareMedical scienceEngineering ethicsPsychologyHealth careMedicinePsychiatryPsychotherapistMedical educationPolitical scienceComputer scienceEngineeringNursingHistory

Abstract

fetched live from OpenAlex

Abstract Through a case narrative set in the near future, this chapter explores some of the cultural and values issues that are raised by recent advances in genetics and associated personalised medicine. On first inspection, these advances might be thought to resolve or at any rate ameliorate the values issues that arise in the context of shared clinical decision-making as the basis of personalised mental health practice in genetic counselling. On the contrary, however, as the case narrative illustrates, the values issues are considerably amplified. This is an instance of the ‘Science Driven’ principle of values-based practice: that the practical impact of advances in medical science and technology is to widen patients’ choices and with choices go values. The result is that advances in medical science and technology drive the need for enhanced values-based as well as evidence-based practice in responding to the challenges presented by personalised clinical care. The emerging resources for responding to these challenges in the context of psychiatric genetic counselling are described.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.004
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Other · Consensus signal: Other
Teacher disagreement score0.006
Threshold uncertainty score0.036

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0030.004
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0050.017
Scholarly communication0.0050.005
Open science0.0010.003
Research integrity0.0020.005
Insufficient payload (model declined to judge)0.0050.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.276
Teacher spread0.263 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2020
Admission routes1
Has abstractyes

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