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Record W3115714183 · doi:10.1016/j.jaip.2020.12.035

GINA 2020: Potential Impacts, Opportunities, and Challenges for Primary Care

2020· article· en· W3115714183 on OpenAlexaff
Alan Kaplan, Job F. M. van Boven, Dermot Ryan, Ioanna Tsiligianni, Sinthia Bosnic‐Anticevich

Post-publication record

NatureReinstatement
ReasonDate of Article and/or Notice Unknown;Notice - Limited or No Information;Removed;Retract and Replace;Temporary Removal;
Date12/26/2020 0:00
Flagged by OpenAlex?No. Retraction Watch records this, and OpenAlex does not flag it.

Source: Retraction Watch, joined by DOI. OpenAlex records retraction as is_retracted, a boolean over a state space with at least four values, so it cannot express an expression of concern, a correction or a reinstatement; it reports them as false, which reads as “fine”.

Bibliographic record

VenueThe Journal of Allergy and Clinical Immunology In Practice · 2020
Typearticle
Languageen
FieldMedicine
TopicAsthma and respiratory diseases
Canadian institutionsUniversity of Toronto
FundersGrifolsMenarini GroupAstraZeneca AustraliaSanofi AustraliaMylanAstraZenecaChiesi FarmaceuticiRespiratory Effectiveness GroupCovis PharmaBoehringer IngelheimGlaxoSmithKline AustraliaSanofiGlaxoSmithKlineRegeneron PharmaceuticalsNovo NordiskTeva Pharmaceutical IndustriesNovartisPfizer
KeywordsAsthmaMedicineAsthma managementPrimary careInhaled corticosteroidsAsthma exacerbationsIntensive care medicinePediatricsFamily medicineInternal medicine

Abstract

fetched live from OpenAlex

In 2019, it was reported that changes to asthma management reported in the Global Initiative for Asthma (GINA) "…might be considered the most fundamental changes in asthma management in 30 years." These changes refer to the recommendation that the treatment of asthma in adolescents and adults would no longer include short-acting ß 2 -agonist (SABA) only, but that people with asthma should receive either symptom-driven inhaled corticosteroids (ICS)-containing treatment (mild asthma) or daily ICS-containing treatment. The fundamental reason for this shift was driven by concerns about the risks and consequences associated with SABA-only treatment, the need to improve the day-to-day management of asthma symptoms to prevent exacerbations and emergent evidence. These recommendations have subsequently been reinforced and characterized in GINA 2020, and it is reasonable to say that they are significant, not only in terms of an asthma management framework but also as a management approach in practice. This opinion article specifically focuses on opportunities and challenges associated with the implementation of GINA 2020 in primary care practice that need to be recognized and addressed if the shift in asthma treatment paradigm is to be successfully implemented into day-to-day practice.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.022
metaresearch head score (Gemma)0.023
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Commentary · Consensus signal: Commentary
Teacher disagreement score0.041
Threshold uncertainty score0.139

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0220.023
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.002
Bibliometrics0.0010.001
Science and technology studies0.0020.003
Scholarly communication0.0060.004
Open science0.0030.008
Research integrity0.0090.008
Insufficient payload (model declined to judge)0.0410.007

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.073
GPT teacher head0.351
Teacher spread0.279 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations28
Published2020
Admission routes1
Has abstractno

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Same venueThe Journal of Allergy and Clinical Immunology In PracticeSame topicAsthma and respiratory diseasesFrench-language works237,207