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Record W3117659601

Timing and location of tick hox gene expression

2017· article· en· W3117659601 on OpenAlexaffabout
Yusra Batool

Bibliographic record

VenueStudent Research Proceedings · 2017
Typearticle
Languageen
FieldAgricultural and Biological Sciences
TopicVector-Borne Animal Diseases
Canadian institutionsMacEwan University
Fundersnot available
KeywordsHox geneBiologyTickEvolutionary biologyGeneGenomeGeneticsZoologyGene expressionEcology
DOInot available

Abstract

fetched live from OpenAlex

Hox proteins are important regulatory molecules used by almost all animal groups to establish body features during embryonic development. They are produced by a cluster of genes called the hox genes. Since these hox genes are highly conserved across taxa, they can be used to study evolutionary relatedness between different animals and to explain the great diversity of animal body forms observed in nature. The Rocky Mountain wood tick, Dermacentor andersoni is commonly found in parts of southern British Columbia, Alberta and Saskatchewan and can spread diseases like the Rocky Mountain spotted fever and tick paralysis. Research has been conducted on the embryonic development of this tick to aid in understanding its life cycle. The purpose of this study is to examine the timing and location of hox gene expression in D. andersoni embryos, using RT-PCR and In-situ hybridization. It is hypothesized that hox genes will be expressed in the early stages of development when body segments are established and appendages start developing. It is expected that the location of expression will vary for each hox gene examined, based on its location in the tick genome. The data can be used to fill gaps in knowledge about tick hox expression and can provide information on tick evolution. Discipline: Biology Faculty Mentor: Dr. Kevin  Friesen

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.006

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.185
GPT teacher head0.412
Teacher spread0.228 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2017
Admission routes2
Has abstractyes

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