Diffuse and Stringy Fibrosis in a Bilayer Interconnected Cable Model of the Left Atrium
Bibliographic record
Abstract
Interconnected cable models of cardiac tissue are known for their numerical stability and performance at high resolution, their handling of strong anisotropy and their interpretation as network of resistors.Building such as mesh is however not straightforward.We developed an approach for automatic construction of 3D bilayer interconnected cable models from left atrial geometry and epi-and endocardial fiber orientation fields.The model consisted of a series of longitudinal and transverse cables intertwined like fabric threads, with a spatial discretization of 100 µm.Diffuse fibrosis was introduced as random uncoupling of cell-to-cell longitudinal and transverse connections.Stringy fibrosis was intended to represent collagenous septa and was implemented as a random set of longitudinal lines of transverse uncoupling (along cables) with Poisson-distributed length.The range of possible uncoupling percentages was assessed by investigating the percolation limit.This modeling approach was tested by simulating activation maps in normal and fibrotic tissues.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.001 | 0.000 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.001 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".