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Record W3119380823 · doi:10.2147/ijgm.s261139

Impact of Endometriosis on Life-Course Potential: A Narrative Review

2021· review· en· W3119380823 on OpenAlexaff
Stacey A. Missmer, Frank F. Tu, Sanjay K. Agarwal, Charles Chapron, Ahmed M. Soliman, Stephanie E. Chiuve, Samantha Eichner, Idhaliz Flores, Andrew W. Horne, Alexa B. Kimball, Marc R. Laufer, Nicholas Leyland, Sukhbir S. Singh, Hugh S. Taylor, Sawsan As‐Sanie

Bibliographic record

VenueInternational Journal of General Medicine · 2021
Typereview
Languageen
FieldMedicine
TopicEndometriosis Research and Treatment
Canadian institutionsOttawa HospitalUniversity of OttawaMcMaster University
FundersNational Center for Advancing Translational SciencesNational Institute of Diabetes and Digestive and Kidney DiseasesAllerganNational Institutes of HealthNordic Pharma GroupNational Institute for Health and Care ResearchWellbeing of WomenU.S. Department of DefenseSociety for the Study of ReproductionMedical Research CouncilAbbVieSwedish Orphan BiovitrumJ. Willard and Alice S. Marriott Foundation
KeywordsLife course approachQuality of life (healthcare)EndometriosisMedicineMenarcheNarrativeMental healthNarrative reviewGerontologyPsychologyDevelopmental psychologyPsychiatryNursingGynecology

Abstract

fetched live from OpenAlex

Endometriosis may exert a profound negative influence on the lives of individuals with the disorder, adversely affecting quality of life, participation in daily and social activities, physical and sexual functioning, relationships, educational and work productivity, mental health, and well-being. Over the course of a lifetime, these daily challenges may translate into limitations in achieving life goals such as pursuing or completing educational opportunities; making career choices or advancing in a chosen career; forming stable, fulfilling relationships; or starting a family, all of which ultimately alter one's life trajectory. The potential for endometriosis to impact the life course is considerable, as symptom onset generally occurs at a time of life (menarche through menopause, adolescence through middle age) when multiple life-changing and trajectory-defining decisions are made. Using a life-course approach, we examine how the known effects of endometriosis on life-domain satisfaction may impact health and well-being across the life course of affected individuals. We provide a quasi-systematic, narrative review of the literature as well as expert opinion on recommendations for clinical management and future research directions.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.011
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.004
Threshold uncertainty score0.013

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.011
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0020.002
Bibliometrics0.0040.005
Science and technology studies0.0000.000
Scholarly communication0.0020.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0040.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.074
GPT teacher head0.489
Teacher spread0.415 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations209
Published2021
Admission routes1
Has abstractyes

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