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Record W3120155304 · doi:10.21203/rs.3.pex-957/v1

Influence of cannabis exposure in pregnancy on childhood health outcomes: a population-based birth cohort

2020· preprint· en· W3120155304 on OpenAlexaffabout
Daniel J. Corsi, Helen C. H. Hsu, Darine El‐Chaâr, Deshayne B. Fell, Mark Walker

Bibliographic record

Venuenot available
Typepreprint
Languageen
FieldHealth Professions
TopicHomelessness and Social Issues
Canadian institutionsOttawa HospitalUniversity of Ottawa
Fundersnot available
KeywordsCannabisPregnancyMedicineConfoundingCohortPopulationCohort studyEnvironmental healthPrenatal carePsychiatryDemography

Abstract

fetched live from OpenAlex

Abstract Cannabis use in pregnancy has increased, and many women continue to use it throughout pregnancy. With the legalization of recreational cannabis in many jurisdictions, there is concern about potentially adverse childhood outcomes related to prenatal exposure.4 Using the provincial birth registry containing information on cannabis use during pregnancy, we will assemble a large, population-based cohort of children born to mothers in Ontario, with and without prenatal exposure to cannabis from birth to 10 years of age. A series of investigations will examine the health effects of prenatal cannabis exposure on child outcomes using novel methods to address confounding. We will link pregnancy and birth data to provincial health administrative databases to ascertain child neurodevelopmental outcomes. The unique aspect of our proposed research is that we plan to utilize an existing population-based perinatal registry combined with administrative datasets for long-term follow up of children using a rich set of covariates and potential confounders to assess the association with cannabis exposure on pregnancy and perinatal outcomes and into childhood.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.501
Threshold uncertainty score0.995

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.001
Science and technology studies0.0010.000
Scholarly communication0.0010.000
Open science0.0010.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.041
GPT teacher head0.398
Teacher spread0.357 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2020
Admission routes2
Has abstractyes

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