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Record W3120430181 · doi:10.21203/rs.3.rs-37057/v1

Simulated sunlight decreases the viability of SARS-CoV-2

2020· preprint· en· W3120430181 on OpenAlexafffund
Angela Sloan, Todd Cutts, Bryan D. Griffin, Samantha Kasloff, Zachary Schiffman, Mable Chan, Jonathan Audet, Anders Leung, Darwyn Kobasa, Derek R. Stein, Guillaume Poliquin

Bibliographic record

VenueResearch Square (Research Square) · 2020
Typepreprint
Languageen
FieldMedicine
TopicInfection Control and Ventilation
Canadian institutionsUniversity of ManitobaPublic Health Agency of Canada
FundersPublic Health AgencyPublic Health Agency of Canada
KeywordsSunlightCoronavirus disease 2019 (COVID-19)Environmental scienceRelative humidityPopulationSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Human decontaminationTransmissibility (structural dynamics)Environmental engineeringMedicineMeteorologyWaste managementPhysicsOpticsEnvironmental healthEngineering

Abstract

fetched live from OpenAlex

Abstract The novel coronavirus, SARS-CoV-2, has spread into a pandemic since its emergence in Wuhan, China in December of 2019. This has been facilitated by its high transmissibility within the human population and its ability to remain viable on inanimate surfaces for an extended period. To address the latter, we examined the ability of sunlight to degrade SARS-CoV-2 on stainless steel. All assays were performed using a solar simulator at the equivalent of one air mass (i.e. equatorial sun at its Zenith). Heat-controlled experiments were conducted at approximately 34% relative humidity (RH); otherwise, RH decreased with sunlight exposure until a constant temperature was maintained. When initially suspended in tissue culture medium, the virus was rendered non-viable after two hours of sunlight exposure. However, when suspended in an organic matrix designed to mimic bodily secretions, three hours of continuous sunlight was required for complete degradation. From this work, we demonstrate that sunlight represents an effective decontamination method but the speed of decontamination is variable based on the underlying matrix. This information has an important impact on the development of infection prevention and control protocols to reduce the spread of this deadly pathogen.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.016
metaresearch head score (Gemma)0.017
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Meta-epidemiology (narrow), Research integrity
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.202
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0160.017
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.003
Science and technology studies0.0010.002
Scholarly communication0.0000.000
Open science0.0010.003
Research integrity0.0010.008
Insufficient payload (model declined to judge)0.0010.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.220
GPT teacher head0.489
Teacher spread0.268 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2020
Admission routes2
Has abstractyes

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