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Record W3124767363 · doi:10.3389/fphy.2020.616618

Dual-Modal Photoacoustic Imaging and Optical Coherence Tomography [Review]

2021· article· en· W3124767363 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
fundA Canadian funder is recorded on the work.

Bibliographic record

VenueFrontiers in Physics · 2021
Typearticle
Languageen
FieldEngineering
TopicPhotoacoustic and Ultrasonic Imaging
Canadian institutionsUniversity of Waterloo
FundersUniversity of WaterlooNatural Sciences and Engineering Research Council of CanadaMitacs
KeywordsOptical coherence tomographyPhotoacoustic imaging in biomedicineMolecular imagingComputer scienceOpticsBiomedical engineeringTomographyMedical imagingModalitiesOptical imagingMedical physicsMaterials scienceArtificial intelligenceMedicinePhysicsIn vivo

Abstract

fetched live from OpenAlex

Optical imaging technologies have enabled outstanding analysis of biomedical tissues through providing detailed functional and morphological contrast. Leveraging the valuable information provided by these modalities can help us build an understanding of tissues’ characteristics. Among various optical imaging technologies, photoacoustic imaging (PAI) and optical coherence tomography (OCT) naturally complement each other in terms of contrast mechanism, penetration depth, and spatial resolution. The rich and unique molecular-specified absorption contrast offered by PAI would be well complemented by detailed scattering information of OCT. Together these two powerful imaging modalities can extract important characteristic of tissue such as depth-dependent scattering profile, volumetric structural information, chromophore concentration, flow velocity, polarization properties, and temperature distribution map. As a result, multimodal PAI-OCT imaging could impact a broad range of clinical and preclinical imaging applications including but not limited to oncology, neurology, dermatology, and ophthalmology. This review provides an overview of the technical specs of existing dual-modal PAI-OCT imaging systems, their applications, limitations, and future directions.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.923
Threshold uncertainty score0.849

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.005
GPT teacher head0.203
Teacher spread0.198 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it