Wilms' Tumor: Long-Term Effect of Multimodal Treatment on Renal Function
Bibliographic record
Abstract
Patients with Wilms' tumor, a common malignant childhood tumor, have an excellent survival rate. The treatment protocol, which consists of a combination of surgery, chemotherapy, and irradiation, may induce both short- and long-term systemic effects. This paper addresses concerns regarding the effects of treatment on long-term renal function in the survivors of Wilms' tumor. In a retrospective study, the charts of 36 patients treated at the Children's Hospital of Western Ontario were analyzed with respect to the epidemiology and parameters of renal function. It was determined that patients with Stage I disease maintained normal renal function over five years. However, those with Stage III and IV disease exhibited decreased renal function immediately after treatment but regained normal renal function within five years. This investigation clearly establishes the need for future prospective studies of long-term renal function of the remaining kidney in children who have undergone treatment for Wilms' tumor.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.002 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".