MétaCan
Menu
Back to cohort
Record W3126771191 · doi:10.1016/j.eclinm.2021.100727

A global point prevalence survey of antimicrobial use in neonatal intensive care units: The no-more-antibiotics and resistance (NO-MAS-R) study

2021· article· en· W3126771191 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
fundA Canadian funder is recorded on the work.

Bibliographic record

VenueEClinicalMedicine · 2021
Typearticle
Languageen
FieldMedicine
TopicNeonatal and Maternal Infections
Canadian institutionsChildren's Hospital of Eastern OntarioSaint John Regional Hospital
FundersLarner College of Medicine, University of VermontCollege of Medicine Office of Research, Ohio State UniversityUppsala UniversitetSultan Qaboos UniversityHospital de Clínicas de Porto AlegrePontificia Universidade Catolica de CampinasUniversidad Nacional de San LuisSchool of MedicineAmerican University of BeirutNelson Mandela Metropolitan UniversityChildren's Hospital of Eastern Ontario FoundationUniversidade Federal do Rio Grande do SulOhio State UniversityNationwide Children's HospitalFondazione IRCCS Ca' Granda Ospedale Maggiore PoliclinicoYale UniversityUniversity of VermontMerck
KeywordsMedicineAmikacinMeropenemVancomycinAntimicrobial stewardshipGentamicinAntibioticsAntimicrobialPediatricsAntibiotic resistanceGestational ageBirth weightLow birth weightAmpicillinNeonatal intensive care unitIntensive careMoxifloxacinIntensive care medicinePregnancyMicrobiology

Abstract

fetched live from OpenAlex

BACKGROUND: Global assessment of antimicrobial agents prescribed to infants in the neonatal intensive care unit (NICU) may inform antimicrobial stewardship efforts. METHODS: We conducted a one-day global point prevalence study of all antimicrobials provided to NICU infants. Demographic, clinical, and microbiologic data were obtained including NICU level, census, birth weight, gestational/chronologic age, diagnoses, antimicrobial therapy (reason for use; length of therapy), antimicrobial stewardship program (ASP), and 30-day in-hospital mortality. FINDINGS: = 0·02). INTERPRETATION: Global NICU antibiotic use was frequent and prolonged regardless of culture results. NICU-specific ASPs were associated with lower antibiotic utilization rates, suggesting the need for their implementation worldwide. FUNDING: Merck & Co.; The Ohio State University College of Medicine Barnes Medical Student Research Scholarship.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.012
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.012
Threshold uncertainty score0.996

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.012
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.048
GPT teacher head0.345
Teacher spread0.297 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it