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Record W3128602736 · doi:10.22215/etd/2016-11312

The Role of Mitchondria in the Potential Hepatotoxicty Caused by Cadmium Telluride Quantum Dot Nanoparticles

2016· dissertation· en· W3128602736 on OpenAlexafffund
Kathy Nguyen

Bibliographic record

Venuenot available
Typedissertation
Languageen
FieldMaterials Science
TopicNanoparticles: synthesis and applications
Canadian institutionsCarleton UniversityUniversity of OttawaHealth Canada
FundersHealth Canada
KeywordsQuantum dotCadmium telluride photovoltaicsNanotechnologyApoptosisChemistryCytotoxicityReactive oxygen speciesToxicityOxidative stressBiophysicsCell biologyMaterials scienceBiologyBiochemistry

Abstract

fetched live from OpenAlex

Nanotechnology has widespread applications in a variety of fields, thus raising concerns about the potential health risk of nanomaterials.Nanoparticle (NP) toxicity is often linked to their novel physiochemical properties which allow them to be transported across cell membranes or to be taken up into target cells, causing changes in sub-cellular structures and affecting cellular activity.This thesis focused on quantum dots (QDs) which are engineered NPs of semiconductor structures.Cadmium-based QDs such as cadmium telluride QDs (CdTe-QDs), owing to their unique optical and electronic properties, have gained much interest as emerging fluorophores and are widely used in

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Other · Consensus signal: none
Teacher disagreement score0.001
Threshold uncertainty score0.005

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.007
GPT teacher head0.238
Teacher spread0.231 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2016
Admission routes2
Has abstractyes

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