MétaCan
Menu
Back to cohort
Record W3128776966 · doi:10.21742/ajnnia.2020.4.1.01

Detecting Drug-Drug Interaction (DDI) over the Social Media using Convolution Neural Network Deep Learning

2020· article· en· W3128776966 on OpenAlexaff
Kelechi Iwuorie, Sabah Mohammed

Bibliographic record

VenueAsia-Pacific Journal of Neural Networks and Its Applications · 2020
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicBiomedical Text Mining and Ontologies
Canadian institutionsLakehead University
Fundersnot available
KeywordsWord embeddingComputer scienceArtificial intelligenceConvolutional neural networkClassifier (UML)Machine learningFeature vectorFeature learningSupport vector machineArtificial neural networkSemEvalRepresentation (politics)Word (group theory)Natural language processingDeep learningEmbeddingTask (project management)

Abstract

fetched live from OpenAlex

Drug-Drug Interaction (DDI) detection is a challenging problem for drug manufacturers, drug regulatory authorities, and medical professionals alike.It is impossible to run trials or be aware of every single case involving an entire population.Research in the use of social media data is currently gaining attention, and with the application of machine learning techniques has been successfully applied in businesses.This paper presents a project extracting DDI from biomedical text using a Convolutional Neural Network (CNN) classifier.The classifier is trained on the SemEval 2013 DDIExtraction challenge dataset and aims to automatically learn the best feature representation on the input of the given task.Different models have been proposed, which make use of position embeddings in combination with word embeddings trained on the machine learning model to learn features.Word embeddings are necessary for providing dense vector representation of words that can be trained, but a large amount of data is required to train an effective vector representation of words.To compensate for the lack shortage of data, the CNN model is trained on a pre-trained PubMed word embedding, which provides a vector dimension of size 200 for the representation of each word.This project aims to provide a trained CNN model for which vector representation of words is provided by weights that have been trained for medical text classification purposes.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.006
Threshold uncertainty score0.012

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0030.002
Science and technology studies0.0000.000
Scholarly communication0.0010.002
Open science0.0000.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.024
GPT teacher head0.279
Teacher spread0.255 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2020
Admission routes1
Has abstractyes

Explore more

Same venueAsia-Pacific Journal of Neural Networks and Its ApplicationsSame topicBiomedical Text Mining and OntologiesFrench-language works237,207