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3D variability analysis: Resolving continuous flexibility and discrete heterogeneity from single particle cryo-EM

2021· article· en· 1,072 citations· W3131760520 on OpenAlex· 10.1016/j.jsb.2021.107702

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian affiliationAn author listed a Canadian institution. This is the only route the usual frame has.
Canadian funderA Canadian agency funded it. The work may carry no Canadian affiliation at all.

Machine scores (provisional)

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Opus teacher head0.010
GPT teacher head0.323
Teacher spread
0.313 · how far apart the two teachers sit on this one work
Validation status
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Abstract

No abstract. This is not a gap in this database — OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

The record

Venue
Journal of Structural Biology
Topic
Advanced Electron Microscopy Techniques and Applications
Field
Biochemistry, Genetics and Molecular Biology
Canadian institutions
University of TorontoVector Institute
Funders
Vector InstituteGovernment of OntarioNatural Sciences and Engineering Research Council of CanadaCanadian Institute for Advanced Research
Keywords
Cryo-electron microscopyBiological systemFlexibility (engineering)SpliceosomeComputer scienceMolecular biophysicsDomain (mathematical analysis)PhysicsAlgorithmBiophysicsChemistryRNABiologyRNA splicingMathematics
Has abstract in OpenAlex
no