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Record W3132567065 · doi:10.3390/pr9020360

Multi-Objective Optimizations of Non-Isothermal Simulated Moving Bed Reactor: Parametric Analyses

2021· article· en· W3132567065 on OpenAlexaff
Jian Wang, Yan Li, Jun Xu, Weifang Yu, Ajay K. Ray

Bibliographic record

VenueProcesses · 2021
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicProtein purification and stability
Canadian institutionsWestern University
Fundersnot available
KeywordsIsothermal processSortingPlug flowMulti-objective optimizationThermodynamicsParametric statisticsThroughputChemistryMathematical optimizationMaterials scienceProcess engineeringComputer scienceMathematicsAlgorithmEngineeringPhysicsStatistics

Abstract

fetched live from OpenAlex

Simulated moving bed reactor (SMBR), a multicolumn multifunctional integrated reactor system, which can be exploited with on-site adsorptive separation to enhance conversion of equilibrium-limited reversible chemical reaction. In this article, for generality, a dimensionless SMBR model was developed and effects of five representative temperature distributions among different zones on the performance of an SMBR for reversible reaction in the general form of a reactant decomposed to two products were evaluated based on simultaneous maximization of unit throughput and product purity. Multipliers were applied to adjust some of the model parameters such that different operation modes can be compared under various conditions in the parametric space. The multiobjective optimization problems were solved using the non-dominated sorting genetic algorithm. All simulations were carried out using FORTRAN codes. The results showed that both kinetics and adsorptive separation play important roles in SMBR. When kinetics is fast or adsorptive potency of the reactant is higher than the desired product (B) but lower than byproduct (C), non-isothermal operation can significantly improve unit throughput. On the contrary, feed concentration and reaction enthalpy have minor effects on the optimal solutions. Decision variables based on flow rate ratios and internal concentration profiles were used to explain the trends of Pareto optimal solution.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: Simulation or modeling
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.005
Threshold uncertainty score0.010

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0010.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.034
GPT teacher head0.336
Teacher spread0.302 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2021
Admission routes1
Has abstractyes

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