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Record W3135515631 · doi:10.1158/1557-3265.adi21-ia-22

Abstract IA-22: Automated treatment planning and quality assurance in radiation oncology

2021· article· en· W3135515631 on OpenAlexaff
Thomas G. Purdie

Bibliographic record

VenueClinical Cancer Research · 2021
Typearticle
Languageen
FieldMedicine
TopicRadiomics and Machine Learning in Medical Imaging
Canadian institutionsPrincess Margaret Cancer Centre
Fundersnot available
KeywordsRadiation oncologyMedical physicsQuality assuranceRadiation treatment planningMedicineRadiation therapyProcess (computing)Radiation TherapistQuality (philosophy)Radiation doseComputer scienceNuclear medicineRadiologyPathology

Abstract

fetched live from OpenAlex

Abstract The delivery of radiation for the treatment of cancer is a complicated process that requires both clinical and technical expertise to ensure radiation treatments are safe and effective. Sub-optimal radiation treatments have the potential to result in significant detriment to the patient and several studies have shown radiation treatments, which deviate from established clinical guidelines, result in worse patient outcomes. Therefore, the current radiation treatment process requires substantial multi-disciplinary resources to both generate and verify radiation treatments are of high-quality. In this talk, a previously validated machine learning platform customized for radiation oncology will be presented. The method automatically learns based on data from thousands of previously treated patients which relationships and patterns in radiation oncology image and treatment data and has been applied for automated data mining activities, automated quality assurance to support expedited radiation treatment review, and for radiation dose prediction to develop new radiation treatments by best deciding where dose should be placed and how dose should be delivered without requiring any manual intervention. Therefore, the method can be used to both generate personalized radiation treatments and to quantitatively score radiation treatments for quality and classify radiation treatments that have errors. The automated platform can readily be integrated into current clinical process to improve efficiency in the radiation treatment planning and plan review processes and to better utilize the vast data we have to ensure we are providing patients with highly personalized radiation treatments. Citation Format: Thomas G. Purdie. Automated treatment planning and quality assurance in radiation oncology [abstract]. In: Proceedings of the AACR Virtual Special Conference on Artificial Intelligence, Diagnosis, and Imaging; 2021 Jan 13-14. Philadelphia (PA): AACR; Clin Cancer Res 2021;27(5_Suppl):Abstract nr IA-22.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.004
metaresearch head score (Gemma)0.012
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.010
Threshold uncertainty score0.020

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0040.012
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.001
Science and technology studies0.0010.001
Scholarly communication0.0030.001
Open science0.0020.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0050.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.270
GPT teacher head0.638
Teacher spread0.368 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2021
Admission routes1
Has abstractyes

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