Effect of Ginger-Naproxen on Knee Osteoarthritis: A Clinical Study
Why this work is in the frame
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Bibliographic record
Abstract
Objective: To evaluate clinical efficacy and safety of ginger with naproxen, in treating knee osteoarthritis.Study design and setting: Randomized clinical trial conducted in medicine department OPD of National Medical Center,Karachi from 21st September 2018 till 31st March 2019.Methodology: This study was conducted on 60 patients of knee osteoarthritis. After written informed consent, the patientswere randomized to two groups. Group A received tablet naproxen 500mg and capsule ginger 550mg, twice daily and groupB was given tablet naproxen 500mg twice daily. Total 53 patients finished the study (group A: n=27 and group B: n=26).Baseline pain (Visual Analogue Scale) and Western Ontario and McMaster Universities Osteoarthritis index (WOMAC)scores were noted at the beginning of study and reassessed after 6 weeks of the intervention. Safety profile of the drugswas assessed by observing adverse effects. Independent t-test was applied to check difference between the two groups.Statistical analysis was performed using SPSS version 23.0. P-value < 0.05 was considered as statistically significant.Results: Before the intervention no significant difference was observed in two groups. However significant difference wasobserved between the groups in pain (p=0.019) and WOMAC (p=0.020) scores after 6 weeks of intervention. Moreoverthere was no significant difference (p=0.914) in occurrence of adverse effects between the two groups at the end of 6 weeksof study.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.003 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it