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DUGRA: Dual-Graph Representation Learning for Health Information Networks

2020· article· en· W3137164726 on OpenAlexafffund
Qifan Wang, Benjamin C. M. Fung, Patrick C. K. Hung

Bibliographic record

Venuenot available
Typearticle
Languageen
FieldComputer Science
TopicMachine Learning in Healthcare
Canadian institutionsOntario Tech UniversityMcGill University
FundersCanada Research Chairs
KeywordsComputer scienceGraphMedical diagnosisArtificial intelligenceOntologyDomain knowledgeMachine learningFeature learningCurse of dimensionalityTheoretical computer scienceData mining

Abstract

fetched live from OpenAlex

With the rapidly growing volume and variety of Electronic Health Records (EHR) data, deep-learning models exhibit state-of-the-art performance for many predictive tasks in the health domain. To overcome the challenge of high dimensionality in EHR data, many representation learning methods have been proposed to learn low-dimensional diagnosis representations. Another challenge is how to effectively incorporate the domain knowledge, such as the International Classification of Diseases (ICD) medical ontology, into the learned embeddings. Albeit the medical ontology is a knowledge graph, none of the existing methods take advantage of Graph Neural Network (GNN), which has demonstrated its ability in other domains. The problem is that a GNN with multiple hidden layers, which are required to propagate information from the leaf of the medical ontology graph to the root, dilutes the differences among the nodes, degrading the quality of the learned embeddings. In this paper we introduce a densely connected graph derived from the original ontology graph to tackle the problem. Furthermore, to model the information in patient records, we construct a single co-occurrence graph based on the co-occurrence of diagnoses and a patient's diagnosis history. Experimental results show that the diagnosis embeddings learned from our model, DUal-GRAph Representation Learning (DUGRA), outperform the current state-of-the-art models in terms of diagnosis prediction accuracy.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: Simulation or modeling
GenreCandidate signal: Methods · Consensus signal: none
Teacher disagreement score0.882
Threshold uncertainty score0.378

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.001
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.031
GPT teacher head0.328
Teacher spread0.298 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2020
Admission routes2
Has abstractyes

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