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Record W3138911480 · doi:10.1093/scipol/scab014

Drawing Lines in the Sand? Paths Forward for Triggering Regulation of Gene-Edited Crops

2021· article· en· W3138911480 on OpenAlexaff
Sara Nawaz, Milind Kandlikar

Bibliographic record

VenueScience and Public Policy · 2021
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicCRISPR and Genetic Engineering
Canadian institutionsUniversity of British Columbia
Fundersnot available
KeywordsExtant taxonCorporate governanceSpellFace (sociological concept)TRACE (psycholinguistics)Emerging technologiesPolitical scienceBiotechnologyEngineering ethicsRisk analysis (engineering)BusinessBiologySociologyComputer scienceEngineeringEvolutionary biologySocial science

Abstract

fetched live from OpenAlex

Abstract Researchers are making use of new gene-editing techniques in medicine, bioenergy, industrial biotechnology, and beyond, and the field of crop breeding is no exception. These techniques, which differ from genetic modification techniques, spell difficult questions for regulatory oversight: will current rules-of-play apply, or do new techniques necessitate fundamental shifts in regulations? Thus far, little explicit attention has focused on the fundamental yet elusive questions of which technical specifics currently trigger regulation of gene-edited crops, and where different jurisdictions ‘draw’ this line. Here, we trace these regulatory lines across key jurisdictions. We argue that extant regulatory definitions are crumbling in the face of emerging technologies and assert that this breakdown poses a threat to responsible governance. Drawing upon insights from responsible research and innovation, we propose a shift away from technically based regulatory approaches and toward more risk-targeted oversight based on broader societal and ecological implications.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.048
metaresearch head score (Gemma)0.048
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesScience and technology studies
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: Theoretical or conceptual
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.996
Threshold uncertainty score0.255

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0480.048
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.001
Science and technology studies0.0040.029
Scholarly communication0.0170.014
Open science0.0040.008
Research integrity0.0120.014
Insufficient payload (model declined to judge)0.0070.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.320
Teacher spread0.307 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designTheoretical or conceptual
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations6
Published2021
Admission routes1
Has abstractyes

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