Bibliographic record
Abstract
Acute delirium has been reported associated with beta-blocker treatment, including propranolol, atenolol, and metoprolol. We report the first reported case of acute onset of acute delirium in a patient treated with carvedilol with complete reversal after treatment withdrawal. The patient was hospitalized for an acute coronary syndrome with left ventricular systolic dysfunction, treated with percutaneous coronary intervention. He developed acute delirium shortly after starting carvedilol on his third hospital day. Other causes of delirium were excluded, and the delirium resolved within 24 hours of carvedilol discontinuation. Carvedilol is an alpha 1 - and beta-adrenergic antagonist with moderate lipid solubility that is eliminated by hepatic metabolism. Given the moderate lipophilicity, carvedilol could certainly penetrate the central nervous system. Our case suggests that carvedilol should be considered among the medications that may cause acute organic brain syndrome. J Med Cases. 2013;4(11):732-733 doi: https://doi.org/10.4021/jmc1523w
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.004 |
| Meta-epidemiology (narrow) | 0.003 | 0.002 |
| Meta-epidemiology (broad) | 0.002 | 0.002 |
| Bibliometrics | 0.004 | 0.003 |
| Science and technology studies | 0.005 | 0.002 |
| Scholarly communication | 0.003 | 0.004 |
| Open science | 0.002 | 0.004 |
| Research integrity | 0.008 | 0.005 |
| Insufficient payload (model declined to judge) | 0.003 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".