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Record W3146125287 · doi:10.21203/rs.2.18184/v1

The Local Burden of Disease for Non-Rheumatic-Acquired Valvular Heart disease in Iran, North Africa and Middle East from 1990 to 2017: Findings from a Sub-Analysis of the Global Burden of Disease Study 2017

2019· preprint· en· W3146125287 on OpenAlexaff
Aziz Rezapour, Samad Azari, Negar Omidi, Masoud Behzadifar, Jalal Arabloo, Vahid Alipour, Nicola Luigi Bragazzi

Bibliographic record

VenueResearch Square (Research Square) · 2019
Typepreprint
Languageen
FieldHealth Professions
TopicGlobal Health and Epidemiology
Canadian institutionsYork University
FundersInstitute for Health Metrics and EvaluationIran University of Medical SciencesBill and Melinda Gates Foundation
KeywordsMedicineMiddle EastIncidence (geometry)Years of potential life lostDemographyDiseaseMortality rateBurden of diseaseDisease burdenvalvular heart diseaseEnvironmental healthLife expectancyPopulationGeographyInternal medicine

Abstract

fetched live from OpenAlex

Abstract Background: Cardiovascular diseases (CVDs) are one of the main causes of mortality and a major barrier to sustainable development, being the main cause of “Disability-Adjusted Life Years” (DALYs), “Years of Life lost” (YLLs) and “Years Lived with Disability” (YLDs). Among CVDs, one of the most common and treatable CVD is non-rheumatic-acquired valvular heart disease (NRVD). However, in some countries such as Iran, the burden of NRVD is almost unknown because previous studies have focused mostly on the burden of ischemic heart disease, heart failure and other cardiovascular diseases. Method: Using data from the 2017 “Global Burden of Disease study”, we compared the number of deaths, DALYs, YLLs, YLDs, incidence and prevalence trends for NRVD in Iran, North Africa and Middle East since 1990 to 2017. Results: Our study yielded 3 major results: 1) a higher rate of death in Iran compared with North Africa, the Middle East and globally; 2) a higher increase in DALYs, YLLs, and YLDs in Iran in comparison with North Africa, the Middle East, and globally from 1990 to 2017; and 3) vast differences in increasing rates of prevalence and incidence of NRVD in Iran compared with the global trends from 1990 to 2017. The significant difference in the prevalence rate of NRVD in Iran versus global rate can be due to the higher growth rates of aging and the co-morbidities associated with NRVD, such as hypertension. Conclusion: Iranian health policy- and decision-makers should allocate significant resources for their diagnosis, treatment and management.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.018
metaresearch head score (Gemma)0.024
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Meta-epidemiology (narrow), Science and technology studies, Research integrity
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.170
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0180.024
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0030.001
Bibliometrics0.0020.004
Science and technology studies0.0020.002
Scholarly communication0.0000.000
Open science0.0040.007
Research integrity0.0010.003
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.250
GPT teacher head0.491
Teacher spread0.241 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2019
Admission routes1
Has abstractyes

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