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Cancer and Diet

2012· article· en· W3146536122 on OpenAlexvenueno aff
Kenneth Lundström

Bibliographic record

VenueJournal of Pharmacy and Nutrition Sciences · 2012
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicNutrition, Genetics, and Disease
Canadian institutionsnot available
Fundersnot available
KeywordsNutrigenomicsDiseaseCancerCancer preventionEpigeneticsIntervention (counseling)GenomicsMedicineBiologyBiotechnologyBioinformaticsGenomeGeneticsInternal medicineGene

Abstract

fetched live from OpenAlex

Intervention in food intake has been demonstrated to play an enormous role in both prevention and treatment of disease. Numerous studies indicate a clear link between cancer and diet. The substantial development of sequencing technologies has resulted in access to enormous amounts of genomics information, which resulted in the establishment of nutrigenomics as an emerging approach to link genomics research to studies on nutrition. Increased understanding has demonstrated how nutrition can influence human health both at genetic and epigenetic levels. Dramatic dietary modifications have proven essential in reducing risk and even prevention of cancer. Moreover, intense revision of diet in cancer patients has revealed significant changes in gene expression and also has provided therapeutic efficacy even after short-term application. Obviously, a multitude of diets have been evaluated, but probably the common factor for achieving both prophylactic and therapeutic responses is to consume predominantly diets rich in fruits, vegetables, fish and fibers and reduced quantities of especially red meat. Despite encouraging findings on how dietary modifications can prevent disease and restore health, there are a number of factors which complicate the outcome. There are variations in response to dietary changes depending on age and gender. Furthermore, ethnic, social and geographic circumstances play an important role.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.012
Threshold uncertainty score0.040

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0010.001
Scholarly communication0.0020.001
Open science0.0000.001
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0120.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.035
GPT teacher head0.364
Teacher spread0.329 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2012
Admission routes1
Has abstractyes

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