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Record W3147597688

Comparison of Chitosan-lactic Acid-poly vinyl alcohol and Chitosan-hydroxyapatite Composite Membrane as Wound Healing Accelerator

2019· article· en· W3147597688 on OpenAlexaff
Goutam Thakur, Kunal Pal, Subrata Pal, Smritinath Chakraborty, Arfat Anis

Bibliographic record

VenueTrends in Biomaterials and Artificial Organs · 2019
Typearticle
Languageen
FieldMedicine
TopicWound Healing and Treatments
Canadian institutionsDalhousie University
Fundersnot available
KeywordsChitosanVinyl alcoholMembraneWound healingMaterials scienceLactic acidWound dressingFibroblastComposite numberBiomedical engineeringChemical engineeringComposite materialChemistrySurgeryMedicineBiochemistryPolymerBacteriaIn vitroEngineering
DOInot available

Abstract

fetched live from OpenAlex

Wound healing is a complex biochemical process and may be promoted by moist wound dressings, which helps in maintaining a suitable micro-environment favorable for migration and proliferation of fibroblast cells. Chitosan has been used by many researchers to develop various wound healing products. The current study deals with the development of chitosan-poly (vinyl alcohol) blended membrane and chitosan-hydroxyapatite composite membrane. The membranes were prepared using lactic acid as solvent. The developed membranes were characterized for their mechanical strength hemocompatibility. Membranes demonstrated significantly different mechanical strength and hemocompatibilty. Further, preliminary results indicated that the developed membranes could be tried as wound dressing materials. The afore-mentioned membranes were used as wound dressing materials for the treatment of surgically induced wounds in matured Sprague-Dawley rats. The wound healing results indicated that the healing rate was faster with the chitosan-hydroxyapatite membrane

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.002

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.046
GPT teacher head0.367
Teacher spread0.321 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2019
Admission routes1
Has abstractyes

Explore more

Same venueTrends in Biomaterials and Artificial OrgansSame topicWound Healing and TreatmentsFrench-language works237,207