Research progress in structure-activity relationship of classIIa bacteriocin producing from lactic acid bacteria
Bibliographic record
Abstract
Bacteriocin produced by lactic acid bacteria( LAB) is a kind of polypeptide or protein with antimicrobial activity,which can inhibit harmful bacteria for human body and can be biodegraded and digested by human body.Class Ⅱa bacteriocin produced by lactic acid bacteria is class Ⅱ bacteriocin which has N- terminal conserved sequence and can inhibit Listeria monocytogenes strongly.Owing to the stable physical and chemical properties of class Ⅱ a bacteriocins,class Ⅱ a bacteriocins have been a hot topic recently,therein,the structure- activity relationship of class Ⅱ a bacteriocin producing from lactic acid bacteria is a difficulty and challenge. For this reason,the structure- activity relationship of classⅡa bacteriocin producing from lactic acid bacteria has been widely studied in recent years. In this paper,the structure,and the structure- activity relationship of classⅡ a bacteriocin producing from lactic acid bacteria were reviewed comprehensively and systematically,and then the current main problems and future research directions were pointed out.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".