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Record W3150491710 · doi:10.1101/2021.03.24.21252471

Inequities in childhood anaemia in Mozambique: results from multilevel Bayesian analysis of 2018 National Malaria Indicator Survey

2021· preprint· en· W3150491710 on OpenAlexaff
Nazeem Muhajarine, Daniel Adedayo Adeyinka, Mbate Matandalasse, Sergio Chicumbe

Bibliographic record

VenuemedRxiv · 2021
Typepreprint
Languageen
FieldMedicine
TopicIron Metabolism and Disorders
Canadian institutionsUniversity of SaskatchewanSaskatchewan Health
Fundersnot available
KeywordsMalariaGeographyPublic healthEnvironmental healthDemographyMultilevel modelMedicinePopulationCross-sectional studySocioeconomics

Abstract

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Abstract Introduction Childhood anaemia is a common public health problem worldwide. The geographical patterns and underlying factors of childhood anaemia have been understudied in Mozambique. The objectives of this study were to identify the child-, maternal-, household-, and community-level determinants of anaemia among children aged 6-59 months, and the contribution of these factors to the variation in childhood anaemia at the community level in Mozambique. Methods This is a cross-sectional study that utilized data of a weighted population of 4,141 children aged 6-59 months delivered by women between 15-49 years of age, from the 2018 Mozambique Malaria Indicator Survey. Multilevel Bayesian linear regressions identified key determinants of childhood anaemia. Spatial analysis was used to determine geographic variation of anaemia at the community level and areas with higher risks. Results The overall national prevalence of childhood anaemia was 78-80.3%. There was provincial variation with Cabo Delgado province (86.2%) having highest prevalence, and Maputo province (70.2%) the lowest. Children with excess risk were mostly found in communities that had proximity to provincial borders: Niassa-Cabo Delgado-Nampula tri-provincial border, Gaza-Inhambane border, Zambezia-Nampula border, and provinces of Manica and Inhambane. Children with anaemia tended to be younger, males, and at risk of having malaria because they were not sleeping under mosquito nets. In addition, children from poor families and those living in female-headed households were prone to anaemia. Conclusion This study provides evidence that anaemia among children aged 6-59 months is a severe public health threat across the provinces in Mozambique. It also identifies inequity in childhood anaemia—worse among communities living close to the provincial borders. We recommend interventions that would generate income for households, increase community-support for households headed by women, improve malaria control, build capacity of healthcare workers to manage severely anaemic children and health education for mothers. More importantly, there is need to foster collaborations between communities, districts and provinces to strengthen maternal and child health programmes for the severely affected areas. What is already known? Nearly two billion people are anaemic, affecting mostly poor women and children. Anaemia, a co-morbidity with other major health conditions, frequently is less prioritized. Sustainable Development Goals 2 and 3, formulated to tackle hunger/food insecurity and attain optimal health/wellbeing, respectively, currently have no specific target for monitoring global progress for anaemia among children. What are the new findings? Twenty-four percent of children (6-59 months) had anaemia classified as mild, 50% moderate and 7% severe. Childhood anaemia showed spatial variation across the communities—especially in the provincial border regions--and provinces in Mozambique; they were younger, males, at risk of having malaria, from poor families and lived in female-headed household. What do the new findings imply? Anaemia among children could be effectively reduced through malaria prevention, e.g. bed netting. This report of anaemia at community and district level provides baseline data and can guide targeted implementation of the 2025 Mozambique National Development Plan. Interventions needed that generate income for households, increase community-support for households headed by women, improve malaria control, build capacity of healthcare workers to manage severely anaemic children and health education for mothers.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.007
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.411
Threshold uncertainty score0.818

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.007
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.002
Science and technology studies0.0010.000
Scholarly communication0.0010.000
Open science0.0000.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.031
GPT teacher head0.295
Teacher spread0.264 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations2
Published2021
Admission routes1
Has abstractyes

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