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Record W3154286410 · doi:10.1038/s41598-021-87978-2

Knee loading in OA subjects is correlated to flexion and adduction moments and to contact point locations

2021· article· en· W3154286410 on OpenAlexafffund
Ali Zeighami, Raphaël Dumas, Rachid Aïssaoui

Bibliographic record

VenueScientific Reports · 2021
Typearticle
Languageen
FieldEngineering
TopicMuscle activation and electromyography studies
Canadian institutionsÉcole de Technologie Supérieure
FundersFonds de Recherche du Québec - SantéNatural Sciences and Engineering Research Council of CanadaLabEx PRIMESUniversité de LyonCanadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of CanadaAgence Nationale de la Recherche
KeywordsMedicineGaitKnee flexionCoronal planeTreadmillCorrelationContact forceGait analysisAnatomyOrthodonticsPhysical medicine and rehabilitationPhysical therapyMathematicsGeometryPhysics

Abstract

fetched live from OpenAlex

Abstract This study evaluated the association of contact point locations with the knee medial and lateral contact force (F med , F lat ) alterations in OA and healthy subjects. A musculoskeletal model of the lower limb with subject-specific tibiofemoral contact point trajectories was used to estimate the F med and F lat in ten healthy and twelve OA subjects during treadmill gait. Regression analyses were performed to evaluate the correlation of the contact point locations, knee adduction moment (KAM), knee flexion moment (KFM), frontal plane alignment, and gait speed with the F med and F lat . Medial contact point locations in the medial–lateral direction showed a poor correlation with the F med in OA (R 2 = 0.13, p = 0.01) and healthy (R 2 = 0.24, p = 0.001) subjects. Anterior–posterior location of the contact points also showed a poor correlation with the F med of OA subjects (R 2 = 0.32, p < 0.001). Across all subjects, KAM and KFM remained the best predictors of the F med and F lat , respectively (R 2 between 0.62 and 0.69). Results suggest different mechanisms of contact force distribution in OA joints. The variations in the location of the contact points participate partially to explains the F med variations in OA subjects together with the KFM and KAM.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.472
Threshold uncertainty score0.378

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.226
Teacher spread0.216 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations28
Published2021
Admission routes2
Has abstractyes

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