Development of a New Experimental Model for Investigating Osseointegration of Titanium Mini-screws Placed Intraorally
Bibliographic record
Abstract
A novel in-vivo pilot study was developed using the rabbit mandibular diastema to evaluate the effect of implant micro- and nano-surface topography on the rate of osseointegration. Six rabbits received one titanium mini-screw from both topographies in each diastema. Two rabbits were euthanized at 6, 22 and 85d post-implantation. Harvested mandibles were measured and processed for reverse torque, microCT, SEM and histological analyses. At 22 days, the nano- surface screws had higher mean torque values but both topographies reached nearly identical mean values after 85 days. Localized areas of crestal bone resorption were seen around all screw heads at 22 days. Sub-periosteal bone formation lateral to the screw heads led to complete coverage of the screws at 85 days. The epithelium of the overlying mucosa was parakeratinized stratified squamous. This intra-oral animal model is suitable to study osseointegration.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.001 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".