A deep learning‐based model for characterization of atherosclerotic plaque in coronary arteries using optical coherence tomography images
Bibliographic record
Abstract
PURPOSE: Coronary artery events are mainly associated with atherosclerosis in adult population, which is recognized as accumulation of plaques in arterial wall tissues. Optical Coherence Tomography (OCT) is a light-based imaging system used in cardiology to analyze intracoronary tissue layers and pathological formations including plaque accumulation. This state-of-the-art catheter-based imaging system provides intracoronary cross-sectional images with high resolution of 10-15 µm. But interpretation of the acquired images is operator dependent, which is not only very time-consuming but also highly error prone from one observer to another. An automatic and accurate coronary plaque tagging using OCT image post-processing can contribute to wide adoption of the OCT system and reducing the diagnostic error rate. METHOD: In this study, we propose a combination of spatial pyramid pooling module with dilated convolutions for semantic segmentation to extract atherosclerotic tissues regardless of their types and training a sparse auto-encoder to reconstruct the input features and enlarge the training data as well as plaque type characterization in OCT images. RESULTS: The results demonstrate high precision of the proposed model with reduced computational complexity, which can be appropriate for real-time analysis of OCT images. At each step of the work, measured accuracy, sensitivity, specificity of more than 93% demonstrate high performance of the model. CONCLUSION: The main focus of this study is atherosclerotic tissue characterization using OCT imaging. This contributes to wide adoption of the OCT imaging system by providing clinicians with a fully automatic interpretation of various atherosclerotic tissues. Future studies will be focused on analyzing atherosclerotic vulnerable plaques, those coronary plaques which are prone to rupture.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".