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Record W3158833611 · doi:10.1101/2021.05.04.21256134

Automated Medical Chart Review for Breast Cancer: A Novel Natural Language Processing Software System

2021· preprint· en· W3158833611 on OpenAlexaff
Yifu Chen, Lucy Hao, Vito Z. Zou, Zsuzsanna Hollander, Raymond T. Ng, Kathryn V. Isaac

Bibliographic record

VenuemedRxiv · 2021
Typepreprint
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicBiomedical Text Mining and Ontologies
Canadian institutionsPrevention of Organ FailureUniversity of British Columbia
Fundersnot available
KeywordsWorkflowPipeline (software)Computer scienceContext (archaeology)SoftwareChartBreast cancerHealth careArtificial intelligenceData scienceMedicineCancerDatabaseStatistics

Abstract

fetched live from OpenAlex

Abstract The incoming health records to the BC Cancer Registry are processed between two to three years behind real-time. In response, we developed a Natural Language Processing (NLP) software to automate the electronic chart review workflow. For the same task that costs hundreds of hours of trained labour, our pipeline extracts data within minutes. During preliminary evaluation, an MD student yielded 93.0% and 98.2% accuracies on a sample of operative and pathology breast cancer documents (for a total number of 2,563 data points processed). In comparison, our prototype achieved 89.6% and 91.4% accuracies, respectively. Future plans include improving the performance of the pipeline and eventually adapt it to accepting a more comprehensive range of electronic health records across cancer types and diseases. In the context of BC’s digital healthcare transformation initiatives, this customized software may provide time and cost savings for both the Registry and cancer researchers.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.007
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.007
Threshold uncertainty score0.014

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.007
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.001
Science and technology studies0.0010.000
Scholarly communication0.0020.002
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0040.003

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.016
GPT teacher head0.321
Teacher spread0.305 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2021
Admission routes1
Has abstractyes

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