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Immunological response of dairy cattle housed at an Ontario animal exhibit to vaccination with Escherichia coli O157 type III secreted proteins

2012· article· en· W3159686168 on OpenAlexaboutno aff
Glenn G. Smith, Susan E. Goebel, Louis A. Guilbault, Louisa J. Zak, Xiaogang Li

Bibliographic record

VenueThe Bovine Practitioner · 2012
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicEscherichia coli research studies
Canadian institutionsnot available
Fundersnot available
KeywordsVaccinationEscherichia coliAntibodyTiterBooster doseBiologyImmunologyAntibody titerMedicineMicrobiologyVeterinary medicineBiochemistry

Abstract

fetched live from OpenAlex

Interventions to reduce on-farm risk are important to help decrease the likelihood that the public will come into contact with Escherichia coli O157. Dairy cattle housed at an Ontario animal exhibit were immunized against E. coli O157, and their blood was tested to measure antibody titers to type III secretory proteins in the vaccine. Data collected during this retrospective study supports the conclusions that all animals, including young calves, immunologically responded to vaccination. At the end of a nine-month study period, those animals which received a two-dose vaccination protocol had similar antibody titers to the type III secretory proteins as those administered a three-dose protocol, and all animals immunologically responded to a single annual booster dose of vaccine.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.610
Threshold uncertainty score0.404

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.023
GPT teacher head0.285
Teacher spread0.262 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2012
Admission routes1
Has abstractyes

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