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Record W3160306886 · doi:10.1101/2021.05.15.21257261

Systematic Review and Meta-analysis on COVID-19 Vaccine Hesitancy

2021· preprint· en· W3160306886 on OpenAlexaboutno aff
Iman Aboelsaad, Dina Mohamed Hafez, Abdallah Almaghraby, Shaimaa Abdulaziz Abdulmoneim, Samar O. El-Ganainy, Noha Alaa Hamdy, Ehsan Akram Deghidy, Ahmed El-Sayed Nour El-Deen, Ehab Elrewany, A Khalil, Karem Mohamed Salem, Samar Kabeel, Yasir Ahmed Mohammed Elhadi, Ramy Shaaban, Amr Alnagar, Eman Ahmad Fadel Elsherbeny, Nagwa Ibrahim El-Feshawy, Mohamed Mostafa Tahoun, Ramy Mohamed Ghazy

Bibliographic record

VenuemedRxiv · 2021
Typepreprint
Languageen
FieldSocial Sciences
TopicVaccine Coverage and Hesitancy
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineMeta-analysisCase fatality rateCoronavirus disease 2019 (COVID-19)Publication biasRandom effects modelDemographyFamily medicineInternal medicineEpidemiologyInfectious disease (medical specialty)

Abstract

fetched live from OpenAlex

Abstract Background: The presented meta-analysis was developed in response to the publication of several studies addressing COVID-19 vaccines hesitancy. We aimed to identify the proportion of vaccine acceptance and rejection, and factors affecting vaccine hesitancy worldwide especially with the fast emergency approval of vaccines. Methods: Online database search was performed, and relevant studies were included with no language restriction. A meta-analysis was conducted using R software to obtain the random effect model of the pooled prevalence of vaccine acceptance and rejection. Egger’s regression test was performed to assess publication bias. Quality assessment was assessed using Newcastle-Ottawa Scale quality assessment tool. Results: Thirty-nine out of 12246 articles met the predefined inclusion criteria. All studies were cross-sectional designs. The pooled proportion of COVID-19 vaccine hesitancy was 17% (95% CI: 14-20) while the pooled proportion of COVID-19 vaccine acceptance was 75% (95% CI: 71-79). The vaccine hesitancy and the vaccine acceptance showed high heterogeneity (I 2 =100%). Case fatality ratio and the number of reported cases had significant effect on the vaccine acceptance as the pooled proportion of vaccine acceptance increased by 39.95% (95% CI: 20.1-59.8) for each 1% increase in case fatality (P<0.0001) and decreased by 0.1% (95% CI: -0.2-0.01) for each 1000 reported case of COVID-19, P= 0.0183). Conclusion: Transparency in reporting the number of newly diagnosed COVID-19 cases and deaths is mandatory as these factors are the main determinants of COVID-19 vaccine acceptance.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.035
metaresearch head score (Gemma)0.085
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Meta-analysis · Consensus signal: Meta-analysis
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.035
Threshold uncertainty score0.186

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0350.085
Meta-epidemiology (narrow)0.0030.002
Meta-epidemiology (broad)0.0190.043
Bibliometrics0.0090.007
Science and technology studies0.0010.001
Scholarly communication0.0050.002
Open science0.0020.002
Research integrity0.0030.002
Insufficient payload (model declined to judge)0.0040.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.077
GPT teacher head0.362
Teacher spread0.284 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designMeta-analysis
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations24
Published2021
Admission routes1
Has abstractyes

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