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Dynamics of the HIV Epidemics among Male Injecting Drug Users Using Agent-Based Modeling

2021· article· en· W3162001926 on OpenAlexaff
Le Tt, Lim Hj, N Shojaati

Bibliographic record

VenueAustin Journal of HIV/AIDS Research · 2021
Typearticle
Languageen
FieldMedicine
TopicHIV, Drug Use, Sexual Risk
Canadian institutionsUniversity of Saskatchewan
FundersFHI 360U.S. President’s Emergency Plan for AIDS ReliefUnited States Agency for International Development
KeywordsHuman immunodeficiency virus (HIV)MedicineNeedle sharingEpidemiologyEnvironmental healthIntervention (counseling)DrugDemographyVirologyPharmacologyInternal medicinePsychiatry

Abstract

fetched live from OpenAlex

Background: Although Injecting Drug Users (IDUs) carry a disproportionate burden of HIV, little is known about the dynamics of the HIV epidemics among IDUs. Objective: This study aimed to characterize the dynamics of the HIV epidemic among IDUs and the effects of alternative HIV prevention intervention strategies using Agent-Based Modeling (ABM). Methods: ABM was constructed using key behavioral risks. The HIV/STI Surveillance study was utilized to create datasets for simulation. Different intervention scenarios were simulated and compared. Results: Lowering needle sharing level among IDUs resulted in the largest reductions in both HIV prevalence and the cumulative number of HIV infections over time in all simulated populations. The majority of the reductions occurred when needle sharing declined from the baseline level to 40% and 30%, respectively. Conclusion: ABM may well complement traditional epidemiological regression-based analysis in providing important insights into the complex dynamics of the HIV epidemics among IDUs.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.004
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: Simulation or modeling
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.042
Threshold uncertainty score0.083

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.004
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0010.000
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.152
GPT teacher head0.423
Teacher spread0.271 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2021
Admission routes1
Has abstractyes

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