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Record W3166627107 · doi:10.21203/rs.3.rs-559074/v1

Energetic Glaucoma Segmentation and Classification Strategies using Depth Optimized Machine Learning Strategies

2021· preprint· en· W3166627107 on OpenAlexaff
ELIZABETH JESI, Shabnam Mohamed Aslam, GS Ramkumar, M. Sujatha, A Anushya, Mary Subaja Christo

Bibliographic record

VenueResearch Square · 2021
Typepreprint
Languageen
FieldMedicine
TopicRetinal Imaging and Analysis
Canadian institutionsSt. Jerome's University
Fundersnot available
KeywordsGlaucomaAffectionBlindnessOptometryMedicineOphthalmologyDiseaseOptic nervePsychologyPathologySocial psychology

Abstract

fetched live from OpenAlex

Abstract Glaucoma is a major threatening cause, in which it affects the optical nerve to lead a permanent blindness to individuals. The major causes of Glaucoma are high pressure to eyes, family history, irregular sleeping habits and so on. These kinds of causes leads to Glaucoma easily as well as the affection to such disease leads a heavy damage to the internal optic nervous system and the affected person will get permanent blindness within few months. The eye fluid called aqueous humor is getting blocked inside due to Glaucoma, in normal cases sometimes the fluid comes out from the eye via mesh perspective channel, but this Glaucoma blocks that channel and causes the fluid to getting locked inside and provides the permanent blockage inside. So, that the eyes are getting severe affections such as infection, random blindness in initial stages and so on. The World Health Organization analyzes and reports nearly 80 million people around the globe are affected due to some form of Glaucoma. The major problem with this disease is it is incurable, however, the affection stages can be reduced and maintain the same level of affection as it is for the long period but it is possible only earlier stages of identification. This Glaucoma causes structural affection to the eye ball and it is complex to estimate the cause during regular diagnosis. In medical terms, the Cup to Disc Ratio (CDR) is minimized to the Glaucoma patients suddenly and leads a harmful damage to one's eye in severe manner. The general way to identify the Glaucoma is to take Optical Coherence Tomography (OCT) test, in which it captures the uncovered portion of eye ball (backside) and it is an efficient way to visualize diverse portions of eyes with optical nerve visibility is shown clearly. The OCT images are mainly used to identify the diseases like Glaucoma with proper and robust accuracy levels. In this paper, a new methodology is introduced to identify the Glaucoma on earlier stages called Depth Optimized Machine Learning Strategy (DOMLS), in which it adapts the new optimization logic called Modified K-Means Optimization Logic (MkMOL) to provide best accuracy in results and the proposed approach assures the accuracy level of more than 96.2% with least error rate of 0.002%. This paper focuses on the identification of early stage of Glaucoma and provides an efficient solution to people in case of affection by such disease using OCT images. The exact position point out is handled by using Region of Interest (ROI) based optical region selection, in which it is easy to point the Optical Cup (OC) and Optical Disc (OD). The proposed algorithm of DOMLS proves the accuracy levels in estimation of Glaucoma and shows the practical proofs on resulting section in clear manner.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.016
Threshold uncertainty score0.033

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.001
Science and technology studies0.0010.001
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0020.001
Insufficient payload (model declined to judge)0.0060.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.106
GPT teacher head0.434
Teacher spread0.328 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations18
Published2021
Admission routes1
Has abstractyes

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