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Record W3171348149 · doi:10.1101/2021.06.11.21258244

A row-generation approach for simultaneous multiple needle trajectory planning in radiofrequency ablation

2021· preprint· en· W3171348149 on OpenAlexaff
Shefali Kulkarni-Thaker, Dionne M. Aleman, Aaron Fenster

Bibliographic record

VenuemedRxiv · 2021
Typepreprint
Languageen
FieldEngineering
TopicAdvanced machining processes and optimization
Canadian institutionsRobarts Clinical TrialsUniversity of Toronto
Fundersnot available
KeywordsPairwise comparisonEllipseTrajectoryThermal ablationScalabilityComputer scienceSet (abstract data type)Radiofrequency ablationInteger programmingAblationAlgorithmMathematicsArtificial intelligencePhysicsMedicine

Abstract

fetched live from OpenAlex

Abstract Radiofrequency ablation is a thermal therapy for moderately-sized cancerous tumors. A target is killed with high temperatures obtained due to the current passed through one or more electrodes (needles) inserted into it. The needles’ trajectory must be meticulously planned to prevent interference with dense organs like bone or puncturing of critical structures like veins. By approximating the thermal lesion to an ellipse, we predefine several valid needle trajectories and then solve an integer programming model to identify pairwise valid needle positions, that meet clinical criteria, using a variation of the classic set cover model. To improve the models’ tractability and scalability, we use row generation-based decomposition techniques that determines pairwise validity using two different types of cuts. Finally, we analyze target and organ-at-risk (OAR) damage using several thermal damage models. Our method is tested on 12 liver targets: three targets each with four different surgical margins. We show promising results that meet clinical guidelines while obtaining full target coverage.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: Simulation or modeling
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.642
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.029
GPT teacher head0.255
Teacher spread0.226 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2021
Admission routes1
Has abstractyes

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