P500 Assessing physical activity, fatigue and quality of life in an outpatient cohort of IBD patients
Bibliographic record
Abstract
Abstract Background Inflammatory bowel disease (IBD) has a substantial impact on quality of life (QoL). This can further be affected by modifiable psychosocial and lifestyle factors, like physical activity (PA). In the current study, we aimed to determine whether PA activity levels were associated with patient and disease characteristics, fatigue and QoL in IBD patients. Methods In this cross-sectional study, consecutive adult IBD outpatients were included. PA was assessed by the Short QUestionnaire to ASsess Health-enhancing physical activity (SQUASH). Patients were considered to have adequate PA levels when exercising with moderate intensity during minimal 30 minutes for at least five days per week according to the Dutch Standards for Healthy Physical Activity. Body composition was assessed by body mass index (BMI) and fat-free mass using BodPod. Fatigue was measured with the Shortened Fatigue Questionnaire (SFQ) and QoL was determined using the SF-36. Patient and disease characteristics, fatigue, and QoL between patients with and without adequate PA levels were analyzed by a student’s t-test or X2-test when appropriate. Results Of the 200 patients (139 Crohn’s disease (CD), 61 ulcerative colitis (UC)), 53.3% were female, and 21.5% were active smoker. Mean disease duration was 11.4 [SD 9.9] years, and 28.6% had an exacerbation at inclusion. The Dutch Standards for Healthy Physical Activity were not met by 41.7%. CD patients (53.2%) were less likely to have adequate PA levels compared to UC (70.0%) patients (p=0.028). There were no other significant differences in patient and disease characteristics stratified by adequate PA level (i.e. sex, active smoking, age at inclusion, disease duration, Montreal classification, previous bowel resection, and disease activity). BMI and fat-free mass index were not associated with PA levels. However, patients not meeting PA standards were significantly more tired compared to patients meeting the standards (mean 17.4 [SD 7.0] vs. 13.5 [SD 7.2], p=0.015), and had lower physical and mental component scores (PCS: mean 43.5 [SD 9.7] vs. 46.0 [SD 8.5]; MCS: mean 46.2 [SD 11.3] vs. 52.3 [SD 9.5]) for QoL, reaching significance for SF-36 MCS (p=0.012). Conclusion IBD outpatients with low physical activity levels showed significantly higher fatigue and lower quality of life scores, regardless of disease characteristics. More research is necessary to identify contributing factors to further improve patients’ well-being by holistic management.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.001 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".