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Mapping Microvascular Network Geometry in 3D

2008· article· en· W3174276914 on OpenAlexaff
Graham Fraser, Daniel Goldman, Stephanie Milkovich, Christopher G. Ellis

Bibliographic record

VenueThe FASEB Journal · 2008
Typearticle
Languageen
FieldMedicine
TopicCardiovascular Health and Disease Prevention
Canadian institutionsWestern University
Fundersnot available
KeywordsComputer sciencePosition (finance)VisualizationMATLABTracking (education)Computer visionNetwork modelVolume (thermodynamics)Artificial intelligenceGeometrySimulationComputer graphics (images)Mathematics

Abstract

fetched live from OpenAlex

The objective is to develop a novel mapping software package using MATLAB to reconstruct microvessels in 3‐dimensions for use in oxygen transport modeling schemes. A single optical imaging system is used to collect experimental in vivo data (hemodynamics and oxygen saturation). Vessels are selected from video sequences and functional still images using automated edge tracking and depth information, collected during the experiment, to construct the 3D network. Simple user driven commands allow the connection of vessel segments and the creation of bifurcations. Built in registration and calibration improves accuracy of relative vessel position and allows vessels to span across multiple focal planes and fields of view. Resulting output provides a simple and versatile array that accurately describes 3D network geometry. The final network visualization (see figure) represents vessels as variable diameter tubes that are scaled accurate to the bounding volume. Networks can be rotated and manipulated in 3D to verify network connections and vessel continuity. The network and corresponding hemodynamic and SaO 2 data can then be easily integrated into computational oxygen transport models.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.003
Threshold uncertainty score0.011

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0030.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.020
GPT teacher head0.254
Teacher spread0.234 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2008
Admission routes1
Has abstractyes

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