Peripheral Edema in an Individual with Treatment Resistant Major Depressive Disorder Treated with Olanzapine/Fluoxetine Combination: PERIPHERAL EDEMA INDUCED BY OLANZAPINE/FLUOXETINE COMBINATION
Bibliographic record
Abstract
Olanzapine/fluoxetine combination therapy is a widely prescribed antipsychotic-antidepressant regimen for treatment resistant depression and is reported to have a side effect of peripheral edema. The theoretical underpinnings of peripheral edema in association with olanzapine/fluoxetine combination therapy are still unclear. Although peripheral edema associated with olanzapine/fluoxetine combination is rarely reported, the mechanism of drug interaction and effect on cytochrome P450 enzymes may induce it. We review the case of a middle-aged patient, who presented with peripheral edema after the administration of olanzapine/fluoxetine combination therapy.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".