MétaCan
Menu
Back to cohort

Sensitivity of forearm critical power to acute manipulation of perfusion pressure

2013· article· en· W3174875664 on OpenAlexaff
J. Mikhail Kellawan, Robert F. Bentley, Jeremy J. Walsh, Jaclyn Moynes, Michael E. Tschakovsky

Bibliographic record

VenueThe FASEB Journal · 2013
Typearticle
Languageen
FieldMedicine
TopicCardiovascular Effects of Exercise
Canadian institutionsQueen's University
Fundersnot available
KeywordsMedicineForearmPerfusionBlood pressureCardiologyInternal medicineNuclear medicineSurgery

Abstract

fetched live from OpenAlex

PURPOSE We tested the hypothesis that manipulating perfusion pressure (PP) impacts forearm critical power (fCP). METHODS 9 healthy young (23 ± 2.6 yrs) males completed 10 min fCP tests in each of arm above (A) and below (B) heart level (forearm PP A < B by ~30 mmHg). fCP (average of force impulse in last 30 s of test), forearm blood flow (FBF; echo and Doppler ultrasound), arterial pressure (MAP; finger photoplethysmography), O 2 consumption (VO 2 ; venous blood samples, Fick eqn) were measured during exercise. RESULTS mean ± SD. Responders (all with compromised fCP in A vs. B; 21 ± 7 vs. 30 ± 6 kg·s, p=0.01) and non‐responders (no compromise to fCP in A vs. B; 29 ± 17 vs. 27 ± 16 kg·s, P=0.14) were identified. Responders exhibited O 2 D compromise in A vs. B (164 ± 60 vs. 178 ± 65 ml O 2 /min, p=0.04), and all had lower VO 2 in A vs. B but this was not statistically significant (VO 2 88 ± 30 ml/min vs. 104 ± 40 ml/min, p=0.12). Non‐responders had no compromise to O 2 D in A vs. B (153 ± 26 vs. 164 ± 28 ml O 2 /min, p=0.53), nor any compromise to VO 2 (99 ± 21 ml/min vs. 106 ± 28 ml/min, p=0.58). No clear pattern regarding pressor or vasodilatory compensation to protect O 2 D was found (Responders A vs. B, ΔFVC p=0.01, ΔMAP p=0.12; Non‐responders A vs. B ΔFVC p=0.22, ΔMAP p=0.37). CONCLUSIONS Reductions in perfusion pressure can reduce forearm critical power in individuals who cannot defend O 2 D. These data highlight the importance of O 2 D to fCP. NSERC

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.466
Threshold uncertainty score0.279

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.011
GPT teacher head0.272
Teacher spread0.261 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2013
Admission routes1
Has abstractyes

Explore more

Same venueThe FASEB JournalSame topicCardiovascular Effects of ExerciseFrench-language works237,207